While not all studies have demonstrated benefit of probiotics for infant colic, many have, particularly in breastfed infants. The latest study (J Pediatr 2015; 166: 74-78) shows that “administration of L reuteri DSM 17938 significantly improved colic symptoms by reducing crying and fussing times in breastfed Canadian infants.”
This study was conducted between 2012-2014 and enrolled 52 infants. These infants were randomized to either probiotics or placebo; the study was double-blind as well.
- For the 21 day study: Total average crying and fussing times for probiotic group was 1719 ± 750 minutes compared with 2195 ± 764 minutes in the placebo group. (P=0.028)
- At the end of the study, the probiotic group crying/fussing for 60 minutes per day compared with 102 minutes/day in the placebo group. (P=0.045)
Take-home message: In breastfed infants, the probiotic L reuteri DSM 17938 reduced crying.
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