What We Are Learning from the “Blue Poop Challenge”

8/21/23 Gastroenterology & Endoscopy News, Open Access! Gut Transit Time Varies by Country

The “Blue Poop Challenge,” (joinzoe.com/bluepoop), a citizen scientist project involving 21,541 volunteers in 17 countries on five continents, is evaluating whole gut transit time (WGTT).  “Findings were based on self-reported WGTT after volunteers consumed blue muffins (84.5 g per muffin x 2, each containing 0.75 g of blue food coloring paste). WGTT was defined as the time elapsing between muffin ingestion and first appearance of blue color in the stool…”

The mean WGTT was 23.9 hours (range, 16.2- 32.0 hours), with country-specific differences, said Dr. Bulsiewicz, reporting the findings at Digestive Disease Week 2023 (abstract Su1612)“…

Fast and slow WGTTs were significantly associated with less healthful diet quality compared with normal WGTT (P<0.001). ‘Lower intakes of plant-based foods were associated with abnormal transit times, which is consistent with the known effect of dietary fiber,‘”

My take: Food-based transit studies are a lot easier to perform than Sitz marker studies. And, of course, who would not want to know if their transit time is faster than their friends?

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Motility in Duchenne Muscular Dystrophy

Briefly noted: D Kraus et al J Pediatr 2018; 194: 238-40.  This study of 7 young adults with Duchenne muscular dystrophy (DMD_ showed normal gastrointestinal motility using a wireless motility capsule (WMC).  The study findings are limited by the small sample size and a selection bias of enrolling only patients capable of swallowing a WMC. This study, however, is important as it supports the notion of ‘enteric muscle sparing’ in DMD.

Related blog post: Don’t Let the Chief of Staff Review This Study

Chattahoochee River