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October 10, 2014 7:00 am
A recent article (JPGN 2014; 59: 317-20) has shown that Neocate Nutra is a good alternative to splenda as a delivery vehicle for budesonide for children with eosinophilic esophagitis.
This retrospective review of 60 children treated with oral viscous budesonide (OVB) who used either splenda (n=46) or with Neocate Nutra (n=14). With regard to budesonide, in patients less than 10 years, the dose was 1 mg/day and older children received 2 mg/day. For splenda patients, 10 packets were used to create a slurry whereas with Neocate Nutra powder the amount was 2.5 cm3 per milligram of budesonide. Followup endoscopy took place at least 10 weeks after the start of treatment.
Key findings:
Limitations of study: small number, retrospective study.
Take-home message: Neocate Nutra is at least as effective as Splenda as mixture with budesonide. In addition, many parents may prefer to avoid Splenda.
Related blog posts:
Posted by gutsandgrowth
Categories: Pediatric Gastroenterology Intestinal Disorder
Tags: budesonide, Eosinophilic esophagitis, Neocate Nutra, oral viscous budesonide, Splenda
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