gutsandgrowth

Home | About Jay Hochman -Pediatric Gastroenterology Blog | Archives

How Many Biopsies Are Sufficient for Diagnosis of Microscopic Colitis?

September 12, 2020 8:59 am

Briefly noted: Microscopic colitis is much more frequent in adults than in children; nevertheless, it is often important to exclude. A recent study (B Virine et al. Clin Gastroenterol Hepatol 2020; 18: 2003-2009. Full text: Biopsies From Ascending and Descending Colon Are Sufficient for Diagnosis of Microscopic Colitis) indicates that biopsies can be limited to the ascending and descending colon.

Methods: This was a retrospective study using biopsies from 101 consecutive patients with MC (52 cases of collagenous colitis, 42 cases of lymphocytic colitis, 7 combined cases),

Key finding:

• In this study, microscopic colitis was detected with 100% sensitivity by analyzing biopsy specimens from the ascending and descending colon

My take: The authors note that previous guidelines have suggested taking 8 biopsy specimens.  Their findings support taking much fewer biopsies.

Related blog post/related article:

• Can Microscopic Colitis Lead to UC or Crohn’s Disease?
• #NASPGHAN19 Postgraduate Course (Part 5)
• Full text PDF: AGA Microscopic Colitis Guideline: GC Nguyen et al. Gastroenterol 2016; 150: 242-6. Technical review DS Pardi et al. Gastroenterol 2016; 150: 247-74. Patient guide: pg 275.

Posted by gutsandgrowth

Categories: Gastroenterology

Tags: collagenous colitis, lymphocytic colitis, microscopic colitis, orofacial granulomatosis

« Older Newer »

One Response to “How Many Biopsies Are Sufficient for Diagnosis of Microscopic Colitis?”

1. […] How Many Biopsies Are Sufficient for Diagnosis of Microscopic Colitis? […]

   By Vedolizumab for Refractory Microscopic Colitis, Plus, Vedolizumab and Serious Infections | gutsandgrowth on February 25, 2022 at 7:00 am

Mobile Site | Full Site

Get a free blog at WordPress.com Theme: WordPress Mobile Edition by Alex King.