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Flu Vaccine in Pregnant Women Did NOT Increase Risk of Autism

September 19, 2020 9:00 am

JV Ludvigsson et al. Annals of Internal Medicine 2020; https://doi.org/10.7326/M20-0167. Full Text: Maternal Influenza A(H1N1) Immunization During Pregnancy and Risk for Autism Spectrum Disorder in Offspring

In total, 39 726 infants were prenatally exposed to H1N1 vaccine (13 845 during the first trimester) and 29 293 infants were unexposed.
Mean follow-up was 6.7 years .
394 (1.0%) vaccine-exposed and 330 (1.1%) unexposed children had a diagnosis of ASD.

My take (borrowed from authors): This large cohort study found no association between maternal H1N1 vaccination during pregnancy and risk for ASD in the offspring.