KE Corcoran et al. J Pediatr Gastroenterol Nutr. 2025;81:1166–1170. Open Access! Long-term gastrointestinal outcomes in pediatric intestinal malrotation patients following operative treatment

It is well-recognized that patients with prior intestinal malrotation have frequent GI symptoms after repair. This retrospective study with 354 children (using TriNetX EMR database) quantitates these problems compared to a control group.

Key findings:

• Symptoms were less severe at years 3-5 post-index for IM group: constipation 29.4%, Abdominal pain 16.4%, Nausea/Vomiting 21.2%, Diarrhea 9.6%, and GERD 22.3%.

My take: While database studies have numerous limitations, it is clear that having a history of intestinal malrotation poses a significant risk of persistent GI symptoms after repair. It will be worthwhile for families to be informed of this at the time of IM repair.

Related blog posts:

• Bowel Obstruction in Newborn
• Dr. Neha Santucci: Management of DGBIs in the Post-Pandemic Era (Part 1)