This full-text link to AJG Practice Guidelines for Celiac Disease 2013 (Am J Gastroenterol 2013; 108:656–676; doi:10.1038/ajg.2013.79) provides 45 evidence-based recommendations for diagnosis and management of celiac disease along with 264 references.
Topics of particular interest
- Whether to test first-degree relatives. The article recommends testing in symptomatic individuals and consideration of testing in asymptomatic individuals
- When to perform genetic testing
- When to use tests besides tissue transglutaminase antibody (TTG IgA) (mainly in children less than 2 years)
- Recommends against use of stool or salivary testing
- How to approach refractory celiac disease
- The limited circumstances which justify followup endoscopy
Potential Reasons for Genetic Testing:
Celiac vs. Gluten Sensitivity:
Bottomline: This practice guideline covers most of the issues dealing with celiac and gluten sensitivity –it is a useful reference.
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