Salvage Therapy and Standard Therapy for H pylori

A recent review (thanks to KT Park for reference) provides helpful resource for treating H pylori infection; this is becoming more important in this era of frequent antibiotic resistance. While this blog has reviewed expert recommendations for treatment, this article provides more insight into salvage treatments.  Table 1 reviews standard quadruple and triple regimens. Table 2 (below) provides dosing in adults for salvage therapy.

Thung, I., et al. (2015), Review article: the global emergence of Helicobacter pylori antibiotic resistance. Alimentary Pharmacology & Therapeutics. doi: 10.1111/apt.13497

Full link: Review article: the global emergence of Helicobacter pylori antibiotic resistance

 

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Related blog posts:

Disclaimer: These blog posts are for educational purposes only. Specific dosing of medications/diets (along with potential adverse effects) should be confirmed by prescribing physician/nutritionist.  This content is not a substitute for medical advice, diagnosis or treatment provided by a qualified healthcare provider. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a condition.

3 thoughts on “Salvage Therapy and Standard Therapy for H pylori

  1. Jay – thanks for the comprehensive useful information – timely as well! A couple of additional points; 1) the majority of the therapies listed in this APT article have not be evaluated in pediatric populations. Thus, dosing should be adapted to the child and on a mg/kg basis. 2) the NASPGHAN-ESPGHAN updated and revised clinical practice guidelines will be published in the next few months – a draft is about to circulated to membership for review. Key in these new guidelines will be considerations of resistance in choosing the antimicrobial therapy regimen – with Clarithromycin resistance having the most significant negative impact on outcome.

  2. Pingback: Quadruple Therapy for Helicobacter Pylori Favored in Toronto Guidelines | gutsandgrowth

  3. Pingback: ACG Guideline for Helicobacter Pylori | gutsandgrowth

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