Another good study on the low FODMAPs diet for irritable bowel syndrome with diarrhea (IBS-D): S Eswaran et al. Clin Gastroenterol Hepatol 2017; 15: 1890-9
This was a propspective, single-blind trial of 92 patients (84 completed study) with IBS-D (65 women) comparing the low FODMAPs diet to a modified diet recommended by the National Institute for Health and Care Excellence (NICE) for 4 weeks. Key findings:
- The low FODMAPs group had larger increase in IBS-QOL score (15.0 vs 5.0). In addition, based on IBS-QOL a meaningful clinical response occurred in 52% compared with 21% in the mNICE group.
- Activity impairment was significantly reduced in the low FODMAPs group; -22.89 compared with -9.44. Anxiety scores decreased as well.
My take: This study indicates that the low FODMAPs diet helps patient with IBS-D, and not just with their GI symptoms.
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