Briefly noted: MD Bellin et al. JPGN 2019; 69: 599-606.

Using the INSPPIRE database with 397 children with either acute recurrent pancreatitis or chronic pancreatitis, the authors examined the frequency of diabetes mellitus (DM).

Key findings:

•  6% (n=24) had a diagnosis of DM. This is 30-fold higher than the general pediatric population
• The group with DM was more likely to have elevated triglycerides (OR 5.21) coexisting autoimmune disease (OR 3.94) or pancreatic atrophy (OR 3.64)
• The group with DM tended to be older with a mean at first diagnosis of acute pancreatitis of 12.9 years compared to 8.7 years in those who did not develop DM

Related blog posts:

• Rapid Progression from Acute Recurrent Pancreatitis to Chronic Pancreatitis In this INSPPIRE study, “within 6 years after the initial acute pancreatitis attack, cumulative proportion with exocrine pancreatic insufficiency was 18% …diabetes mellitus was 7.7%”
• Consensus Pancreatitis Recommendations | gutsandgrowth
• For the pediatric pancreatologists | gutsandgrowth
• Chronic Pancreatitis in Pediatrics -Descriptive Study | gutsandgrowth
• Pancreatitis Update (part 1) | gutsandgrowth

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