F Mori et al. JPGN 2022; 74: 175-179. De Novo Food Allergy in Pediatric Recipients of Liver Transplant
This interesting review has several key points:
- Reported prevalence of food allergy after liver transplant ranges from 5% to 40%
- Younger age at transplantation is a risk factor for developing de novo post-transplant food allergy (dnPTFA)
- Tacrolimus has been implicated as a risk factor for dnPTFA
- Common dnPTFA are the same as in the general population: milk, egg, wheat, peanouts/nuts, fish, and soy
- If the donor has a food allergy, the recipient should be tested within the first months of transplant for food-specific IgE and “it is advisable to introduce the suspected food in a controlled setting”
- Elimination diet is mainstay of treatment. Some individuals may need modification of their immunosuppressive medications
- Provide self-injectable epinephrine in those with food allergy
- Monitoring of specific IgE/skin prick tests is advised
My take: There are increased allergy issues in kids who have had liver transplantation.
Related blog post: Lots of Allergy & Autoimmunity Issues Following Solid Organ Transplantation
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