J Tome et al. Clin Gastroenterol Hepatol 2022; 20: 1085-1094. Open Access: The Epidemiology of Microscopic Colitis in Olmsted County, Minnesota: Population-Based Study From 2011 to 2019
Key points:
- “The overall incidence of MC in Olmsted County, MN, increased from 1985 to 2001, stabilized between 2002 and 2010, and continues to show a plateau between 2011 and 2019.”
- Medications associated with a risk of microscopic colitis (MC) include statins, SSRIs, PPIs, aspirin, other NSAIDs, and histamine H2-receptor antagonists within 3 months of diagnosis. “A recent US multicenter cohort study found an inverse association with PPIs and histamine H2-receptor antagonists when compared with controls with chronic diarrhea; only NSAID use was associated with MC. 31 It is plausible these medications do not cause MC, but instead aggravate diarrhea and bring the diagnosis to clinical attention.”
Related blog post/related article:
- How Many Biopsies Are Sufficient for the Diagnosis of Microscopic Colitis?
- Can Microscopic Colitis Lead to UC or Crohn’s Disease?
- #NASPGHAN19 Postgraduate Course (Part 5)
- Full text PDF: AGA Microscopic Colitis Guideline: GC Nguyen et al. Gastroenterol 2016; 150: 242-6. Technical review DS Pardi et al. Gastroenterol 2016; 150: 247-74. Patient guide: pg 275.
- Microscopic, Lymphocytic and Collagenous Colitis
- Vedolizumab for Refractory Microscopic Colitis, Plus, Vedolizumab and Serious Infections
gutsandgrowth 