Something You Probably Have Not Seen with Celiac Disease and Headaches

An “image of the month” in the NEJM shows the association between celiac disease and occipital calcifications in a 24 year-old with a 10 year history of headaches, here’s the link: 

The course and explanation: Treatment with a gluten-free diet, folic acid supplementation, and carbamazepine was initiated, and the patient’s condition improved, with remission of all symptoms. The combination of celiac disease, epilepsy, and cerebral calcification is a rare condition known as the CEC syndrome. Folate malabsorption is a suggested mechanism


Also, there is a useful patient celiac education page from JAMA Pediatrics & University of Chicago: 

5 thoughts on “Something You Probably Have Not Seen with Celiac Disease and Headaches

  1. Hi,

    I was looking for more info regarding CEC syndrome online & stumbled across your blog. I was wondering how rare this truly is and if you know anyone who has seen patients with this syndrome in Ga or surrounding states? Thank you so much!


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