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March 20, 2015 7:00 am
A recent study (Shitrit AB, et al. Inflamm Bowel Ds 2015; 21: 631-35) highlights the phenomenon of acquiring inflammatory bowel disease (IBD) by moving from a non-developed country to a developed country; the implication is that the changes in environment and diet predispose towards the development of IBD.
This study examined Ethiopian Jews who migrated to Israel. Using a case-control study, the authors compared 32 Ethiopian immigrants to 33 Ashkenazi patients with IBD.
Key findings:
The study discusses the difficulty of diagnosing IBD in rural Africa but speculates that rather than an underdiagnosis of IBD, it is likely to have a true low prevalence of IBD.
Take-home message: It takes many years for the environment exposures to allow for the development of IBD. Additional work is needed to establish the clinical, genetic, and microbial factors that influence the acquisition of IBD in immigrants to developing countries. Understanding the susceptibility of immigrants would have widespread application.
Related blog posts:
Posted by gutsandgrowth
Categories: inflammatory bowel disease, Pediatric Gastroenterology Intestinal Disorder
Tags: Crohn's disease, epidemiology, Ulcerative colitis
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By Increasing Inflammatory Bowel Disease Among U.S. Patients From India | gutsandgrowth on June 8, 2015 at 7:09 am