There has been a lot of interest and conflicting reports about whether antibiotics contribute to obesity. Another interesting study on this theme:
- ET Rogawski et al. JPGN 2017; 65: 350-6.
The authors followed 1954 children twice weekly from birth to 2 years of age as part of the MAL-ED study. There were 8 study sites, including in Bangladesh, India, Brazil, Pakistan, Nepal, South Africa, Peru, and Tanzania. Key finding:
- Antibiotic use before 6 months of age was associated with increased weight from 6 months to 2 years of age.
- Antibiotic use after 6 months did not affect growth.
The authors speculate: “If treatment of infections were the main mechanism, we would expect antibiotic exposure after 6 months to also have an impact.” Thus, they conclude that effects on the microbiome are likely a more important explanation.
My take (borrowed from te authors): “Antibiotic use in low-resource settings” can improve growth, though the long-term consequences are not known. In high-income settings, weight gain secondary to antibiotic exposure is more likely to be detrimental.
Related blog posts:
- NY Times: Frequent antibiotics may make children fatter
- Could antibiotics make you fat? | gutsandgrowth
- Could Obesity Be Cured/Created at Birth with Manipulation of …
- Missing Bacteria in Refractory Malnutrition | gutsandgrowth
- Preterm Neonatal Microbiota and Effect of Perinatal …
- Early Antibiotics and Obesity | gutsandgrowth