Briefly noted: V Ajmera et al. Clin Gastroenterol Hepatol 2018; 16: 1511-20. This study with 285 participants showed that modest alcohol consumption was associated with a lower odds of NASH resolution on biopsy over 4 years compared with no alcohol consumption (OR 0.32). The associated editorial (pg 1404-6) provides a table with 8 studies that reveal conflicting results on this issue.
My take (borrowed from editorial): “Clinicians should not recommend modest drinking” as a way of improving liver health.
Related review article:D Fuster, JH Samet. “Alcohol Use in Patients with Chronic Liver Disease” NEJM 2018; 379: 1251-61. For NAFLD (and all chronic liver disease): “abstinence should be the goal.”
Related blog posts:
- NAFLD Guidance from AASLD 2018
- Concise Review: Fatty Liver in Pediatrics
- Ultrasound Unreliable to Exclude Fatty Liver
- Fatty Liver Disease improved with Exercise
Lake Moraine, Banff
Pingback: Liver Shorts Feb 2019 | gutsandgrowth