1. When You Are Fully Vaccinated 2.Outcomes of Duodenal Atresia and Stenosis

  1. CDC Recommendations: When You’ve Been Fully Vaccinated
  2. GS Bethell et al. JPGN 2021; 72: 239-243. One-year Outcomes of Congenital Duodenal Obstruction: A Population-based Study

This prospective observational study provides helpful outcome data for infants (n=80) born with congenital duodenal obstruction (CDO).

Key findings (also see infographic below):

  • Though there was an 8.4% overall mortality, there were no deaths directly attributed to CDO. 69% had associated anomalies.
  • Median length of stay after repair was 20 days; at 28 days following repair, 76% had been discharged home
  • Failure to achieve full enteral feeds was NOT related to CDO (due instead to other gastrointestinal anomalies). Mean time for full feeds was 13 days post-op; 90% reached full enteral feeds at 28 days.
  • Repair type: 80% had duodenoduodenostomy, 14% had duodenojejunostomy, the others: membrane incision (n=1), membrane resection (n=2), and duodenoplasty (n=2)

My take: This data will inform clinicians of expected outcomes in this population. I hope this cohort is followed long-term to provide more information about long-term outcomes including frequency of pancreatitis.

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