J Chan et al. JPGN 2023; 76: 494-497. Complications and Utility of Gastrointestinal Endoscopy Post Hematopoietic Stem Cell Transplantation: An 11 Year Experience
In this study, sixty-six of 339 (19%) HSCT needed an “endoscopy episode.” Key findings:
- Four of 119 (3%) endoscopies had complications: septic shock (1), duodenal hematoma (1), GI bleeding (1), and colonic perforation (1).
- Fifty-seven of 62 (92%) endoscopy episodes were “clinically useful,” and 41 of 62 (66%) had a change in immunosuppressive treatment.
My take: Endoscopy provides useful information in children following HSCT. However, the consent needs to reflect the much higher risk in this population.
Related blog posts:
- Improved Understanding 18 Years Later
- Liver biopsy risk in children Fox VL, Cohen MB, Whitington PF, Colletti RB. Outpatient liver biopsy in children (n=450). J Pediatr Gastroenterol Nutr 1996;23:213-6. High mortality rate reported, primarily in bone marrow transplant patients
- Must-Read: How to Handle Post-Procedure Fevers
- Adverse Events Following Pediatric Endoscopy –Underestimated Previously
- High Endoscopy Complication Rate After Intestinal Transplantation
- Therapeutic Endoscopy Rarely Beneficial in Infants with Gastrointestinal Bleeding