Roni Rabin, NY Times 3/5/26: Most Patients Keep Weight Off With Fewer GLP-1 Shots, Study Finds
An excerpt:
After 36 weeks of follow-up, most of the patients who spaced out their GLP-1 injections kept the weight off and also maintained health benefits like reduced blood pressure and better blood sugar control…
The study was small, only 34 patients in a relatively homogeneous group — mostly white and privately uninsured… the research, published in February in the journal Obesity, provides a potentially appealing new option for patients who are loath to commit to lifelong weekly injections of a costly medication that may not be covered by insurance and that some fear could have unknown side effects…
The patients reduced the frequency only after achieving their desired weight loss and reaching a weight-loss plateau.
My take: In some patients, less frequent dosing of GLP-1s may be effective as maintenance therapy. Whether this strategy could be applied to the daily oral semaglutide is not clear.
Related blog posts:
- Wegovy Pill Now FDA Approved
- Bariatric Surgery Declines as GLP-1 Medications Rise
- Semaglutide Keeps Weight Off at Four Year Mark
- Weight Gain If Semaglutide Stopped
- The Rise of Oral Obesity Therapies: Semaglutide and Orforglipron
- “You Can’t Outrun a Bad Diet”
- Meds for Obesity: AAP Guidelines
- Semaglutide Keeps Weight Off at Four Year Mark
- Weight Gain If Semaglutide Stopped
- Semaglutide in Adolescent Obesity
- Tirzepatide for Metabolic Dysfunction–Associated Steatohepatitis (MASH) & Uptick in GLP1 Use
- GLP-1 Obesity Medication for 6-11 Year Olds
- AGA Guidance: GLP-1 Receptor Agonists Prior to Endoscopy
- Getting over the Stigma of Medicines for Anxiety/Depression and Obesity
- Tirzepatide: Promotes Impressive Weight loss
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