Z Younossi et al. Liver Transplantation 2026; 32(4):p 549-557. Steatotic liver disease is the dominant indication for liver transplantation in both Europe and the United States: Trends and outcomes in the past 2 decades

Methods: Adult data from 2 large LT registries: the US Scientific Registry of Transplant Recipients (SRTR) and the European Liver Transplant Registry (ELTR), years 2000–2022, were compared. There were 109,048 recipients of transplant from ELTR (30 countries), and 128,765 from SRTR.

Key findings:

• #1 cause in 2022: Alcohol-associated liver disease (ALD) increased: SRTR 15%to 45%, and ELTR 25% to 41%
• #2 cause in 2022: NASH/MASH also increased: SRTR 9% to 28%, and ELTR 5% to 12%
• Chronic hepatitis C decreased: SRTR 40% to 7%, and ELTR 25% to 7%

Related blog posts:

• Liver Transplantation is Getting More Costly in U.S
• Here’s A Bad Idea-Alcohol Consumption on the Day of Liver Transplantation
• How to Lower Pediatric Liver Transplantation Waitlist Mortality
• Screenshots: Peutz-Jeghers Syndrome, Alcohol #1 for Liver Transplantation, Case report Fanconi Syndrome due to Tenofovir Alafenamide (2019)