A recent study (JPGN 2014; 59: 225-28) examined fat-soluble vitamin deficiencies in pediatric patients with newly diagonosed Celiac disease (CD).
Of the 83 patients analyzed between 1995-2012 at the Mayo clinic, the key findings:
- No patients had vitamin A deficiency
- Two patients had vitamin E deficiency. Both of these patients had complete villous atrophy along with a malabsorptive presentation.
- Nine patients had mild-to-moderate vitamin D deficiency (less than the reported frequency in the general pediatric population)
- All of these vitamin deficiencies corrected with gluten-free diet and vitamin supplements.
A limitation of the study was a selection bias as not all children underwent vitamin level measurements.
Take-home message (from authors): “fat-soluble deficiencies are uncommon in children with a new diagnosis of CD. Routine measuring of fat-soluble vitamin levels may not be necessary.”
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