According to a recent study (M Saps et al. JPGN 2018; 66: 387-90), joint hypermobility is not associated with an increased risk of functional gastrointestinal disorders (FGIDs).
From a school-based study of 654 children from a public school in Cali, Columbia, 148 (22.6%) were identified as having an FGID. Among this group, 136 children participated in the study along with 136 age/sex-matched healthy controls. Joint laxity was assessed to establish a Beighton score.
- There was no significant difference in joint laxity between the FGID group and the control group, with OR of 1.03.
The implication of this study is that previous associations between joint hypermobility (JH) and FGIDs could be due to selection bias at tertiary care centers. Alternatively, “it is possible that the association between FGIDs and JH exists, but it is only limited to a subset of patients that consult at specialized clinics.”
My take: This article challenges the idea that JH increases the risk of FGID. Based on this study, if JH is a risk factor, it is hard to detect in a general population.
Related blog post:
- NASPGHAN17 Postgraduate Course (with segment on POTS, joint hypermobility)