In a recent study (C Canova et al. J Pediatr 2018; 198: 117-20) from Padua, Italy compared 1233 individuals with celiac disease to a comparison group of 6167 (from a population-based cohort of >200,000 individuals). In this longitudinal study with a maximum followup of up to 23 years, the authors found no increase risk of fractures in youths diagnosed with celiac disease (HR of 0.87).
- 22 individuals had fractures compared to 128 in the reference population
- Median age of celiac diagnosis was 6 years
- While celiac disease is linked to osteoporosis, “the vast majority of individuals with childhood celiac disease are likely to heal shortly after the introduction of a gluten-free diet.”
My take: Institution of a gluten-free diet for children with celiac disease likely removes the risk of osteoporosis.
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