For PDF copy of slides: NAFLD and NASH

Dr. Zobair Younassi gave a recent virtual grand rounds –here are some of the slides:

Epidemiology:

Natural History:

• Progression of disease is not linear
• Fatty liver disease is a multisystem disorder.  Cardiovascular disease is leading cause of death in patients with fatty liver disease
• Fatigue (~50%) is common with fatty liver disease

Main treatment:

• Weight loss -Mediterranean diet may be helpful
• Exercise
• No FDA-approved treatments, though pioglitizone supported by AASLD for biopsy-proven NASH
• Public health interventions are needed