Below I’ve included a few slides and some notes; my notes may have errors of omission or transcription.

How I Treat Children with Hepatitis C  William Balistreri

Key points:

• The recommendations for pediatric hepatitis C infection have been rapidly-changing due to a large number of recent studies/new direct-acting antivirals.  There are many new treatment options (see HCVguidelines.org); currently available treatment regimens noted below
• All children >3 years of age with HCV should be treated –high cure rates (91-100% SVR) and this leads to long-term improvements in health outcomes
• Test for Hepatitis B before instituting DAA therapy
• Universal screening has been recommended for all adults >18 years.  This omits the pediatric age group; however, if all pregnant women are screened, the majority of pediatric HCV infections could be identified

Related blog posts:

• Medical Progress: Toward Hepatitis C Elimination (Pediatric Treatment Algorithms)
• ‘Crushing it:” Practice Guidance for Hepatitis C
• Resolution: Eradication of Hepatitis C
• Pediatric HCV Guidelines
• “Crushing it:” Two More Pediatric Hepatitis C Trials
• Hepatitis C Infections Increasing -Tied to Opioid Crisis
• Hepatitis C Cure: Too Late for Many | gutsandgrowth