Notes from this year’s Aspen Webinar 2021. This blog entry has abbreviated/summarized some of these presentations. Though not intentional, some important material is likely to have been omitted; in addition, transcription errors are possible as well. The first talk was excellent.
What’s Hot -COVID-19 and the Liver William Balistreri
This lecture covered a ton of information and publications with regard to COVID-19 and the liver.
Key points:
- Numerous studies generally show that liver problems related to COVID-19 are mild, particularly in children
- Most immunosuppression agents do not worsen outcomes with COVID-19 and should not be reduced in autoimmune hepatitis or liver transplantation; the exception, mycophenolate has been associated with worsened outcomes
- Cirrhosis is associated with worse outcomes in patients with COVID-19
- Vaccine response is blunted in immunocompromised patients with 40-50% developing antibody response after two doses of mRNA vaccines and generally lower titers. 3rd dose of vaccine may improve response.
Some of the slides:
Pediatric Data:
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