Positioning Radiology Tests for GI Bleeding

N Sengupta et al. Am J Gastroenterol 2024; 119: 438-449. Open Access! The Role of Imaging for Gastrointestinal Bleeding: Consensus Recommendations From the American College of Gastroenterology and Society of Abdominal Radiology. Thanks to Dr. Benjamin Gold for this reference.

This article was jointly published: Radiology 2024; 310(3):e232298

This article focuses on GI bleeding in adults; it has a lot of useful information about the advantages, disadvantages, techniques and performance date of numerous radiology tests which can help sort out GI bleeding.

CTE identification of a Dieulafoy’s lesion (from Figure 4)
CTE here shows a slowly bleeding angioectasia (arrow), most conspicuous on the delayed phase.

Some of the recommendations for Overt Lower GI Bleeding:

CT Angiography:

Catheter Angiography:

99mTc-RBC Scan

For Suspected Small Bowel Bleeding:

CT Enterography (uses oral contrast). Technique: CTE should be performed using multiphase technique in patients older than 40 years of age where vascular lesions are a common cause for bleeding.

Meckel’s Scan “A Meckel scan can be considered to identify the cause of unexplained intermittent GI bleeding in children and adolescents after negative endoscopic evaluation, including capsule endoscopy if available, and cross-sectional evaluation of the small bowel.”

Radiology compared to capsule endoscopy and balloon-assisted endoscopy The authors discuss the advantages and limitations of radiologic testing versus capsule endoscopy and balloon-assisted endoscopy for small bowel bleeding is provided in Appendix S5

My take: This article provides a good update/review on useful radiologic imaging for GI bleeding. For pediatric GI bleeding, the etiologies are much different and many patients should be evaluated with a Meckel’s scan prior to panendoscopy (depending on the clinical presentation).

Related blog posts:

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Magnetic resonance enterography for Crohn’s disease

Magnetic resonance enterography (MRE) has increasingly been recognized as an effective way to characterize small bowel disease in Crohn’s disease (Inflamm Bowel Dis 2012; 18: 520-28).

In this retrospective pediatric study, 95 patients with Crohn’s disease underwent MRE from 2006-2009.  As expected, terminal ileal disease was the most common site of involvement with 54%; this was followed by ileum with 19%, and jejunum with 17%.  Other findings included solitary jejunal inflammation (3.7%), small bowel stenosis (1.9%) fistula (1%), and abscess (1%).  Specific evidence of inflammation included contrast enhancement, bowel wall thickening or derangement of bowel wall shape.  The images in the article are excellent.

The main advantage of MRE over CT enterography (CTE) is the lack of ionizing radiation.  In addition, MRE can better detect soft tissue contrast suggestive of bowel wall edema.  This helps distinguish acute from chronic inflammation.  Obtaining an MRE is technically more challenging and more costly.  The youngest patient in the study was seven; though the authors note that the youngest patient they have performed MRE was six.

Additional references:

  • More imaging needed?
  • -JPGN 2010; 51: 603.  MRE for suspected IBD.  Useful in pediatric Crohn’s disease.
  • -IBD 2009; 15: 1635. U/S compared favorably with endoscopy in correlating postoperative recurrence with Crohn’s.
  • -Clin Gastro Hepatol 2006; 3: 1221. MRI as accurate in evaluating ileocolonic disease with flareups as endoscopy.
  • -IBD 2004; 10: 452-61. U/S was very helpful in identifying disease and complications.