Cardiac changes with biliary atresia (BA) are surprisingly common– Gastoenterology 2011; 141: 1264-72. In this study, 48 patients with BA, listed for liver transplantation, underwent echocardiography between 2004-2010. The median age was 8 months. Significant increases in left ventricle wall thickness (23% increase) and mass (51% increase) were noted; in addition, functional changes were noted as there was an increase in LV shortening fraction (8% increase). Features of ‘cirrhotic cardiomyopathy’ were evident in 72% of infants (29/40). The authors conclude that these heart changes likely contribute to prolongation of posttransplant hospitalization.
- -J Am Coll Cardiol 2010; 56: 539-49
- -J Hepatol 2010; 53: 179-90.