In a post earlier this week (Four advances for intestinal failure), ethanol locks were discussed. More on information this subject (Pediatrics 2012: 129: 318-29) comes in a meta-analysis. These authors identified 4 retrospective studies in pediatric IF populations. Ethanol locks reduced infections by 81% and line replacements by 72%. The studies in this meta-analysis overlapped with the six studies cited in the previous post. Adverse events were rare and included thrombotic events.
- -JPEN 2012; 36: 36S-42S