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August 22, 2015 9:00 am
A previous study has indicated that maternal probiotic administration was associated with a lower rate of atopic dermatitis. The overall quality of evidence supporting this association is considered low.
A recent study (CK Dotterud et al. JPGN 2015; 61: 200-7) examined the effect on the intestinal microbiota in both mother and child following maternal perinatal probiotic supplementation. This randomized, double-blind trial examined the effect of probiotic administration (or placebo) from 36 weeks of gestation up to 3 months postnatally while breastfeeding. Stool microbiome was examined in both mother and child.
Key findings:
My take: We know very little about probiotics and their effects on the GI tract. We often do not even the basics: which strains? which dosage? optimal timing/when to use? Given the lack of persistent change in the infant’s microbiome, does administration to pregnant mothers really make any sense (outside of research endeavors)?
Posted by gutsandgrowth
Categories: Nutrition, Pediatric Gastroenterology Intestinal Disorder
Tags: atopic dermatitis, microbiome, prenatal, probiotics
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