I started thinking about this question after a recent study (DS Vitale, et al. JPGN 2015; 61: 408-10) examined adherence at a single pediatric center (2010-2012). Adherence indicated “those who attended >80% of scheduled infusions.” Key findings:
- 91.4% adherence rate of patients (n=151 with >4 infusions)
- Adherent patients (n=138) attended an average of 98% of their infusions. Nonadherent patients attended, on average, 76% of their infusions.
- The study provided some preliminary evidence that there was greater acute care use in nonadherent patients.
- There were no demographic features that could predict adherence pattern.
My take: One of the key advantages of infusion therapy is improved and documented adherence. Infusions also provide opportunities to assess patient in a scheduled manner. This study shows that subsets of patients with scheduled infusions have suboptimal adherence — another target for quality improvement!

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