Online Webinar –Annual Aspen Conference  —July 14, 2000

Below I’ve included a few slides and some notes; my notes may have errors of omission or transcription.

Can We Skip Liver Biopsies in Infants with Cholestasis? Jim Squires

Key points:

• Data suggest that cholestasis in infants needs to be defined as direct bilirubin/conjugated bilirubin >0.3 (if TB <5) or 10% if TB >5.
• Identifying cholestasis is challenging as cholestasis occurs in ~1 in 2500 whereas jaundice occurs in 15% of all infants
• Genetic testing (eg. Cholestasis Panel, or exome) needs to be moved up earlier in diagnostic algorithm, after ultrasound completed and after A1AT & biliary atresia considered

Related blog posts:

• Blood test is better than liver biopsy for biliary atresia
• Will We Still Need a Liver Biopsy to Diagnose Biliary Atresia in a Few Years?
• Helpful Review on Biliary Atresia | gutsandgrowth
• Newborn bilirubin measurements for biliary atresia
• Neonatal cholestasis for neonatologists

Not part of webinar: