Two recent articles delve into the topic of Pediatric to Adult Care Transition.
M Katz et al. J Pediatr (Epub head of publication) 2021. African American Pediatric Liver Transplant Recipients Have an Increased Risk of Death After Transferring to Adult Healthcare (Thanks to a friend who shared this reference & congratulations to my Emory colleagues and senior author Nitika Gupta on this publication)
This retrospective study examined 101 patients between 1990 and 2015. 64 had long-term followup data available.
- African Americans had higher rates of death after transfer than patients of other races (44% mor-
tality vs 16%, representing 67% of all cases of death; P = .032)
- 18 of the 64 (28%) died. Of those 18 deaths, 4 (22%) occurred within the first 2 years after transfer, and 10 (55%)
within 5 years of transfer.
- There was a high rate of medication nonadherence in patients who died. ” Death in our cohort was typically caused by chronic rejection and graft failure, with a high frequency of severe infections or bleeding events ultimately causing a patient to die.”
- The average age of transplant in deceased patients was 15. Transplantation in teenage years could be a risk factor as well.
- The authors note that “the years directly after transfer of care from pediatrics to adult medicine are high risk for death and poor patient outcomes. Racial disparities seen in pediatric medicine also hold true after transfer to adulthood.”
H Pearlstein et al. JPGN 2021; 72: 563-568. Predicting Suboptimal Transitions in Adolescents with Inflammatory Bowel Disease
This retrospective study with 104 subjects defined suboptimal transition as “either a return to pediatric care or requiring care escalation within 1 year of transfer.
- 37 (36%) were determined to have a suboptimal transition.
- Risk factors: mental health diagnosis (OR 4.15), medication non-adherence (OR 5.15), public insurance (OR 6.60), and higher Physician Global Assessment score at time of transition (OR 6.64).
Comments: This is a small study and included only 26 patients receiving public insurance, which the authors considered as a proxy measure of socioeconomic status.
My take: These studies show the difficulties and potential deadly outcomes that face these young adults during transition from pediatrics to adult care. In many cases, medication non-adherence is a key factor and can be affected by access to care, insurance coverage, and mental health. Most young adults with serious medical problems probably would benefit from keeping their parents actively involved in their care.
Related blog posts:
- Challenging Assumptions: Self-Management Skills in Adolescents and Poor Outcomes
- Working on Transition Readiness
- Alive and well? 10 years after liver transplantation
- Inequality in Pediatric Health Care | gutsandgrowth
- What’s Missing in Pediatric IBD Care
- AASLD Guideline: Long-Term Care for Pediatric Liver Transplantation | gutsandgrowth