D Burnett et al. JPGN Reports 2021; Free Access: Incidence of Pediatric Eosinophilic Esophagitis and Characterization of the Stricturing Phenotype in Alberta, Canada doi: 10.1097/PG9.0000000000000136
This retrospective study (2015-2018) identified 185 new cases of eosinophilic esophagitis (EoE).
- Eight of 185 (4%) patients had endoscopically confirmed esophageal strictures, 4 of which required mechanical dilation. (The authors note a Dutch study which demonstrated a 14% stricture rate)
- Eleven of 185 (5.9%) patients had more subtle signs of esophageal narrowing, but no focal strictures
- Pain was reported after 15% of all scopes, including 50% of the 28 scopes with focal strictures
- For patients <15 years old living in Edmonton, the incidence over the 4 years was 11.1 cases per 100,000 person years
- EoE was more common in urban setting: incidence 10.6 versus 4.1 per 100,000 person-years, respectively
My take: This article provides useful data on the likelihood of stricturing EoE in the pediatric population in an area with a high incidence of EoE.
Related blog posts:
- Esophageal Hypervigilance and Outcomes in EoE
- New 2020 Eosinophilic Esophagitis Guidelines | gutsandgrowth
- Phase 3 Budesonide Trial
- Head-to-Head: Budesonide vs Fluticasone for Eosinophilic Esophagitis | gutsandgrowth
- Grading Treatment Response in Eosinophilic Esophagitis | gutsandgrowth
- Orodispensable Budesonide Tablets for EoE
- What is EoE?
- EoE Update 2018 (Dr. Seth Marcus)
- 4-14-4 Rule: More Biopsies Needed For EoE Diagnosis
- Best Approach for Identifying Eosinophilic Esophagitis
- Looking Twice for Eosinophilic Esophagitis