F Megraud et al. AJG 2022; doi: 10.14309/ajg.0000000000002045 Open Access: Rates of Antimicrobial Resistance in Helicobacter pylori Isolates From Clinical Trial Patients Across the US and Europe. Resistance rates were established in isolates from 907 participants. Overall, 22.2% were resistant to clarithromycin, 1.2% to amoxicillin, and 69.2% to metronidazole.

O Atia et al. Lancet Gastroenterol Hepatol 2022; DOI:https://doi.org/10.1016/S2468-1253(22)00307-7. Outcomes, dosing, and predictors of vedolizumab treatment in children with inflammatory bowel disease (VEDOKIDS): a prospective, multicentre cohort study

Methods: VEDOKIDS was a paediatric, multicentre, prospective cohort study done in 17 centres in six countries. We report the 14-week outcomes as the first analyses of the planned 3-year follow-up of the VEDOKIDS cohort

Key findings:

• 32 (42%) of 77 children with ulcerative colitis and 21 (32%) of 65 children with Crohn’s disease were in steroid-free and exclusive enteral nutrition-free remission at 14 weeks.
•  In children who weighed less than 30 kg, the optimal drug concentration associated with steroid-free and exclusive enteral nutrition-free clinical remission was 7 μg/mL at week 14, corresponding to a dose of 200 mg/m² body surface area or 10 mg/kg

USAToday 11/14/22: More teens are getting weight loss surgery but some experts think more needs to be done

And of course, an important story from The Onion: Arsonist Worried He Forgot To Turn Stove On Before Leaving House

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