J Llaneras et al. Clin Gastroenterol Hepatol 2021; 19: 1030-37. Etiologies and Features of Acute Viral Hepatitis in Spain

This prospective study of adults collected data from an emergency room of an academic hospital in Barcelona (2014-2018).

Key findings:

• The most common etiologies of acute hepatitis were HBV infection (28%), HEV infection (18%), HCV infection (17%), and HAV infection (14%)
• Approximately one-third of acute hepatitis cases were in immigrants
• The main risk factors of the cohort were sexual risk contact and intravenous drug use; 79% of cases of HAV had sexual risk behavior
• Chronic infections developed in 5/28 patients (18%) with acute HBV infection and 7/17 patients (41%) with acute HCV infection