Do Anti-TNF Agents Reduce Surgeries and Hospitalizations?

Briefly noted:

A recent study (; SK Murthy et al. BMJ indicates that anti-TNF therapy has not been effective in significantly lowering CD-related hospitalizations or surgeries.

Full Text Link (from Eric Benchimol twitter feed): Introduction of anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases: a population-based interrupted time series study)

My take: While big changes in the frequency of these outcomes were not demonstrated in this large study, prior studies, including the RISK study, have shown that anti-TNF therapy can be disease-modifying and reduce the risk of penetrating disease in Crohn’s disease.

Related blog post: CCFA Updates in IBD


2 thoughts on “Do Anti-TNF Agents Reduce Surgeries and Hospitalizations?

  1. Pingback: Anti-TNF Therapy: Might Save Your Health But Not Your Wallet | gutsandgrowth

  2. Pingback: What Happens After The First Anti-TNF Agent Doesn’t Work? | gutsandgrowth

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