Briefly noted: F Humbel et al. Clin Gastroenterol Hepatol 2020; 18: 2019-2029. Association of Alterations in Intestinal Microbiota With Impaired Psychological Function in Patients With Inflammatory Bowel Diseases in Remission
In a prospective study with 171 adults with IBD in remission, the authors combined
- measures of psychological comorbidities and quality of life (QoL)
- microbial analysis with 16S rRNA high-throughput sequencing
Key findings:
- Microbiomes of patients with higher perceived stress had significantly lower alpha diversity
- Anxiety and depressive symptoms were significantly associated with beta diversity
My take: This study adds another dimension to the idea of bidirectionality between psychological well-being and course of inflammatory bowel disease. The microbiome may directly influence both psychological well-being and IBD activity.
Related blog posts:
- Depression Screening for Pediatric Patients with IBD
- Working Together to Improve Outcomes for Children with Inflammatory Bowel Disease | gutsandgrowth
- IBD Depression Screening
- Depression Screening for Pediatric IBD -reviews presentation on this topic with more slides
- Suicide Rate Up 33% in Last 20 Years
- No Exaggeration: Too Many Children Are Dying in the U.S.
- What to Do for Friends and Family Members Who Are Depressed
- IBD Updates: Depression and Crohn’s Disease
- There is No Healthy Microbiome
- Why Does Enteral Nutrition Work for Crohn’s Disease? Is it due to the Microbiome?
