“What Do I Need to Learn Today?”

A recent commentary (GT McMahon. NEJM 2016; 374: 1403-5) provides some perspective on adult learning. In this era of ubiquitous information, developing the right strategy for learning is crucial, not just in medicine but globally. Key points:

  • “Physicians seeking professional development can recognize when they’re actively learning and tend to embrace activities that allow them to do so.”
  • “Many clinicians appreciate learning alongside their peers but may struggle with the feeling that times spent in group educational settings is not efficient or productive enough to be worthwhile.”
  • “CME is most effective in changing physician performance and patient health outcomes if it is interactive.”
  • “Adults prefer education that’s self-directed, based on needs they have identified, goal-oriented, relevant, and practical.”
  • Learning facilitated by working in small groups to solve problems and with interaction (eg. smartphone polls). Other strategies include simulation programs and social media.
  • Working at getting CME to count towards other regulatory burdens (eg. maintenance of board certification), can “reduce the burden on physicians and promote lifelong learning.”

My take (with help from author): Incorporating educational innovation is important to improve physician performance and patient care. “All of that change begins with each of us having the humility and presence of mind to ask ourselves, ‘What do I need to learn today?’”

Vik Muniz Art. George Stinney Jr, the youngest person executed in U.S. at age 14 years. This artwork is composed of hundreds of pictures.

Vik Muniz Art. George Stinney Jr, the youngest person executed in U.S. at age 14 years. This artwork is composed of hundreds of pictures.

GeorgeStinneyJrInfo

Pediatric Nutritionist: Blenderized & Pureed Gtube Diets

A recent Children’s Healthcare of Atlanta Nutrition Support Colloquium provided a terrific update on the use of blenderized and pureed diets via gastrostomy tube.

Here’s the link to the talk (including slides) and a summary on the Pediatric Nutritionist blog site: The Blenderized and Pureed by Gtube Diets

I’ve found these diets to be particularly useful in children with retching.  In addition, these diets can lower costs, reduce other symptoms like constipation, and appeal to parents who desire more typical foods in their child’s diet.

Related blog postNutrition University -Part 1 | gutsandgrowth

Gibbs Gardens

Gibbs Gardens

 

Guidelines for Traveler’s Diarrhea in Adults

Full text: Guidelines on Traveler’s diarrhea in Adults from ACG

Some of the recommendations:

  • -use of oral rehydration if severe diarrhea (especially elderly).  “Most individuals with acute diarrhea…can keep up with fluids and salt by consumption of water, juices, sports drinks, soups, and saltine crackers
  • -against use of probiotics for acute diarrhea except in cases of post antibiotic-associated diarrhea
  • -for use of bismuth subsalicylates to slow stool passage
  • -for use of adjunctive loperamide in patients receiving antibiotics for traveler’s diarrhea (to increase chance for cure)
  • -for antibiotics in traveler’s diarrhea “where the likelihood of bacterial pathogens is high enough to justify the potential side effects of antibiotics”
  • -against antibiotics for community-acquired diarrhea

Table 4 outlines antibiotic selection.

Screen Shot 2016-04-12 at 7.52.47 PM

Disclaimer: These blog posts are for educational purposes only. Specific dosing of medications/diets (along with potential adverse effects) should be confirmed by prescribing physician/nutritionist.  This content is not a substitute for medical advice, diagnosis or treatment provided by a qualified healthcare provider. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a condition.

 

Don’t Let the Chief of Staff Review This Constipation Study

A useful study from Cincinnati (D Klaus et al. J Pediatr 2016; 171: 183-8) provides data on the high prevalence of constipation in Duchenne Muscular Dystrophy. (DMD)  Though, the authors acknowledge that rectal examination was “deferred unless clinically indicated.” I’m fairly certain that the former chief of staff, if asked for input, would have stated that the only two reasons for not doing this part of the exam was “either no rectum or no finger.”

In this prospective cross-sectional study, the authors relied on the Questionnaire on Pediatric Gastrointestinal Symptoms based on Rome-III criteria (QPGS-RIII) to identify constipation.  Based on this questionnaire, 46.7% (56 of 120) of patients with DMD were diagnosed with functional constipation.

  • Traditional features of constipation like bowel movement infrequency of <3/week and hard stools were present in only 16% and 17% respectively.
  • Other features that identified constipation included straining with defecation in 35.1%, painful defecation (27.8%), and clogging toilet (22.6%)
  • The Bristol Stool scale had a low sensitivity for detecting constipation (only 18%) but had a high specificity of 95% if type 1 or 2.
  • Constipation did not increase with age or functional status which makes the concern that this is primarily related to an ineffective bear-down (Valsalva) less likely

My take: Constipation in children with DMD is underreported and often overlooked.  It needs to be considered more carefully at routine visits.

Related posts:

Vik Muniz Art at High Museum

Vik Muniz Art at High Museum

When you look closely at the horse's nose, you can see that this art was completed with toy soldiers

When you look closely at the horse’s nose, you can see that this art was completed with toy soldiers

CDC: Increase in Acute Hep B in Appalachia

MMWR 2016; 65: 47-50. Increases in Acute Hepatitis B Virus Infections — Kentucky, Tennessee, and West Virginia, 2006–2013

An excerpt:

  • During 2006–2013, a total of 3,305 cases of acute HBV infection were reported to CDC from Kentucky, Tennessee, and West Virginia. During 2009–2013, incidence of acute HBV infection increased 114% in these three states, but remained stable in the United States overall
  • Among cases in which at least one risk factor was reported, the proportion of persons reporting injection drug use as a risk factor was significantly greater in 2010–2013, compared with 2006–2009 (75% versus 53%; p<0.001)…the increase was statistically significant only among cases occurring in non-urban counties
  • The findings in this report are subject to …limitations. First, NNDSS is a passive surveillance system, and therefore, unreported cases might have been missed. Second, the current case definition for acute HBV infection captures only symptomatic persons and excludes persons with asymptomatic HBV … Third, … certain populations at high risk (e.g., persons who are incarcerated, homeless, and uninsured) with limited access to care could potentially be underrepresented

My take: Increased drug use appears to be driving an increase in acute HBV in Appalachia. “Evidence-based prevention strategies, including increasing hepatitis B vaccination coverage, testing and linkage to care activities, and education campaigns targeting persons who inject drugs are urgently needed.”

Gibbs Gardens, Ball Ground

Gibbs Gardens, Ball Ground

Hepatitis A Vaccine Should Work for 30 Years

A recent study (PR Spradling et al. Hepatology 2016; 63: 703-11) provided data indicating that the Hepatitis A virus (HAV) vaccine would likely work for 30 years after childhood vaccination.  Much has changed since the implementation of the HAV vaccine.  Since 2000, the number of HAV case in the U.S. has dropped almost 90%, from 13,397 to 1781 in 2013 with the lowest incidence in those ≤18 years.

This study (n=183) examined three groups of Alaska Native children who received a two-dose inactivated HAV vaccine.

  • Vaccine starting at age 6 months (group 1)
  • Vaccine starting at age 12 months (group 2)
  • Vaccine starting at age 15 months (group 3)

Key findings:

  • All participants in groups 2 and 3 through age 10 years were seropositive (anti-HAV ≥ 20 mIU/mL), whereas in group 1 it was >90%.
  • At 15-16 years following vaccination, the seropositivity was 50-75% in group 1 and 67-87% in groups 2 and 3.
  • Using modeling, the overall 30-year anti-HAV seropositivity was predicted to be present in 64% of all participants and 84% of those that were seropositive at 15-16 years.

HAV continues to represent an ongoing threat, despite a reduction in the number of cases.  This is particularly due to unvaccinated travelers and unvaccinated adutls.  In vaccinated adults, a study (Vaccine 2015; 33: 5723-27) inidcates that seropositivity would be present in at least 95% after 30 years and 90% after 40 years.

My take: these data provide reassurance that HAV vaccine’s protection will be durable among those who were vaccinated between 6-21 months of life.

Related blog posts:

Culebra, Puerto Rico

Culebra, Puerto Rico

“The Couric Effect”

A recent commentary (Am J Gastroenterol advance online publication 29 March 2016; doi: 10.1038/ajg.2016.118) by Katie Couric provides a summary of her personal journey as an advocate for preventing colon cancer.

A good read: An Unexpected Turn: My Life as a Cancer Advocate

Here’s an excerpt:

“April is the cruelest month,” T.S. Eliot wrote in “The Waste Land,” and in 1997 it certainly was for my family. That’s when my husband Jay and I discovered he had stage IV colon cancer that had spread to his liver…and the beginning of a 9-month nightmare…

the University of Michigan found that my televised colonoscopy and educational outreach contributed to a sustained 19% increase in the number of colonoscopies performed nationwide. They called it “The Couric Effect”

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Fresh Fruit Study

A study from China has shown benefits associated with increased fresh fruit intake (H Du et al. NEJM; 2016; 374: 1332-43). Abstract Link: Fresh Fruit Consumption and Major Cardiovascular Disease in China

Study methods: 512,891 adults recruited from 2004-2008.  Prospective cohort.

Results: 18% of participants consumed fresh fruit daily.  This group had lower systolic blood pressure (by 4 mm Hg), lower glucose (by 0.5 mmol/L) (both with P<0.001).  The adjusted hazard ratio for cardiovascular death was 0.6 (CI 0.54-0.67), 0.66 for major coronary event, 0.75 for ischemic stroke, and 0.64 for hemorrhagic stroke.

Limitation: Fruit consumption was correlated with socioeconomic status and this may have affected findings even after adjustment due to residual confounding.

My take: While fruit consumption has not been proven to cause better health, daily fruit consumption is associated with better outcomes.

Related blog postEat your veggies…if you don’t want to get sick | gutsandgrowth

Savings with veggies

 

Looking for Value in Medicine

  • Finding Value in Unexpected Places — Fixing the Medicare Physician Fee Schedule.  RA Berenson, JD Goodson. NEJM 2016; 374: 1306-10.
  • When Is It Ethical to Withhold Prevention? TA Farley.  NEJM 2016; 374: 1303-5.

As noted in yesterday’s blog post, after reading these two commentaries I thought a little more about value in pediatric gastroenterology.  These articles though focus on other aspects.  In the first reference, the authors explain the flaws with moving from volume to value-based care.  They note that the medicare physician fee schedule (MPFS) has a powerful influence on physician activities and “their tendency to perform unneeded tests and procedures.”  In fact, the fee schedule heavily contributes to growing shortages of primary care physicians.  Key points:

  • “Two key flaws in the RBVS [resource-based relative value scale] are its substantial misevaluations of physician work and the failure of current service codes to capture the range and intensity of nonprocedural physician activities, known as evaluation and management (E/M) services.”
  • “The MPFS still assumes that it takes nearly 30 minutes to interpret a magnetic resonance image of the brain…typically takes about 10.”  Echocardiogram per MPFS assumes 31 minutes, but takes 5-10 minutes.  For colonoscopy with polyp removal, MPFS assumes 78 minutes, but this is overestimated as well.
  • Valuations depend on AMA-sponsored expert panels…not surprisingly, updates that reduce RVUs are rarely proposed.
  • While the commentary implies that procedural codes are overvalued, it notes that due to complexity of chronic conditions that E/M codes are undervalued.
  • Their conclusion: “implementing new incentives and quality measures in new payment models while maintaining a broken fee schedule is a prescription for failure.”

The second reference bemoans the fact that the medical system will spend enormous amounts of money to prolong the life of an individual with terminal cancer for a few weeks but will not see the imperative of providing adequate prevention measures. Key points:

  • “Many people reject any attempt to put a dollar value on human life…but…limits of funding make it impossible to pay for every conceivable intervention.”
  • Cost-effectiveness is not considered by Medicare in determining treatment.  “For example, treatment of metastatic lung cancer may cost $800,000 per QALY [quality-adjusted life-year], but it is typically provided.  In sharp contrast, primary preventative services are often withheld even if they are highly cost-effective.”
  • Diabetes prevention program focused on exercise and nutrition has QALY costs of $14,000.  Smoking cessation with nicotine-replacement therapy has QALY <$5000.
  • Author’s conclusion: “because withholding primary prevention leads to unnecessary suffering and death, we should be just as creative in finding ways to pay for it” as we do with treatment of all illnesses.

My take: At an individual physician level, we need to keep working to utilize our resources more carefully.  However, at a policy making level, efforts at improving incentives for primary prevention and primary care are needed.

Related blog posts (see yesterday’s post Why are so many Low Value Endoscopies Performed? for related links as well):

Poster on Front of High Museum is reproduction of Vik Muniz piece created from Jelly and Peanut Butter

Poster on Front of High Museum is reproduction of Vik Muniz piece created from Jelly and Peanut Butter